Mobile measurement of microperfusion – MikroFlow

The aim of the project is to design a compact, self-sufficient measurement system for the diagnosis of impaired microcirculation and for the early detection of signs of decompensation in patients of all age groups on a laboratory scale and to carry out initial examinations on patients.

Currently the capillary refill time (CRT) is recorded manually and therefore subjectively, in daily rescue operations and in everyday clinical practice to assess the microcirculation as a (super)vital auxiliary parameter for assessing the patient’s condition.

While conventional measurement methods for recording macrocirculatory conditions (e.g., blood pressure, pulse measurement, pulse oximetry) are widely used, there are few practical, examiner-independent, quantitative, and mobile methods for recording relevant information about microcirculation. An existing discrepancy between insufficient microcirculation (blood flow in organs and

tissues) and normal macrocirculation (blood flow in the large vascular system) can currently only be detected to an insufficient extent. However, disturbances in microcirculation significantly increase organ dysfunction and mortality rates. Previous methods of measuring microcirculation are complex, therefore only used sporadically in clinical and experimental settings, and have limited informative value.

Based on the measurement of capillary refill time, the aim of the project is to design and implement a compact, examiner-independent measurement system for the diagnosis of impaired microcirculation and for the early detection of, for example, fluid deficiency or regional circulatory disorders. The measurement system should be able to transmit the measured data wireless to allow central monitoring.

In this project, a prototype of the mobile sensor head will be developed and initially tested.

Dr.-Ing. Mirko Riedel I last mile semiconductor GmbH

  • Torsten Richter I University Hospital Dresden Carl Gustav Carus and Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology
  • Uwe Vogel I Fraunhofer IPMS
  • Christian Körner I Schmietex Engineering GmbH
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